DDW in Cancer Therapy

Chemotherapy exhibits numerous side effects in anti-tumour therapy. The clinical experiments indicated that deuterium-depleted water (DDW) monotherapy or in combination with chemotherapy was beneficial in inhibiting cancer development. To further understand the potential mechanism of DDW in cancer therapy, we performed a systematic review.

Biological effect of Deuteronation

The biological effects of deuteronation on biological systems. The paper focused on the important enzyme in our mitochondria- ATP synthase as an example.

Deuterium Trafficking

This paper explore the cellular response to the stress that Deuterium caused in the cells. It shed some light on the potential role of certain amyloid proteins (like amyloid beta), the prion protein, huntingtin, and α-synuclein, in disease processes. The results is the accumulation of deposits of protein fibrils, along with lipid membrane components of damaged mitochondria, which may be argues as the mechanism the body devised to sequester deuterium in order to reduce the deuterium burden in the tissues.